Daktarin oral gel is indicated for the treatment of clinically significant oral and gastrointestinal candidiasis "Oral Trush". Miconazole possesses an antifungal activity against the common dermatophytes and yeasts as well as an antibacterial activity against certain gram-positive bacilli and cocci. Its activity is based on the inhibition of the ergosterol biosynthesis in fungi and the change in the composition of the lipid components in the membrane, resulting in fungal cell necrosis.
Dosage and Administration
Infants
For infants less than one year old, one quarter (¼) of a measuring spoon of gel four times daily, or 20 mg/kg/day is recommended.
Children and Adults
Half (½) a measuring spoon of gel four times daily.
NOTE: A measuring spoon (5 mL) is provided with the gel. One spoonful contains approximately 124 mg of miconazole. All spoonful dose volumes should be administered with this spoon
Daktarin oral gel should be placed on the tongue and kept in mouth for as long as possible before swallowing.
When treating infants and younger children it is recommended that the measured dose of gel be given in several portions in the front of the mouth.
Avoid dosing to the back of the throat to prevent obstruction.
With oral thrush in elderly patients where a contributing cause is the dental prosthesis, it is recommended that DAKTARIN oral gel be applied directly to the dentures in the evening and left on overnight.
The treatment should be continued for at least one week after the symptoms have disappeared and generally until all clinical and mycological laboratory tests no longer indicate that active fungal infection is present.
Contraindications
Daktarin oral gel is contraindicated in patients with known hypersensitivity to any of its components and in patients with liver dysfunction.
| 
